News Release

The American Association for Cancer Research provides support for promising cancer scientists

Grant and Award Announcement

American Association for Cancer Research

The American Association for Cancer Research (AACR) offers a number of grants for cancer researchers at various stages in their careers to foster the development of the most promising scientists. This year, the AACR has selected 15 investigators to receive these career development awards and research grants, which total commitments of $915,000. These investigators, scientists who range in level from postdoctoral fellows to assistant professors, were selected through a rigorous and highly competitive process and will be recognized during the AACR's 97th Annual Meeting, to be held April 1-5, 2006, in Washington, D.C.

AACR-GERTRUDE B. ELION CANCER RESEARCH AWARD The AACR–Gertrude B. Elion Cancer Research Award was established in 1993 in honor of the late Nobel Laureate Dr. Gertrude B. Elion, Scientist Emeritus at Glaxo Wellcome Co. and Past President and Honorary Member of the AACR. This award fosters meritorious basic, translational, or clinical cancer research by a tenure-track scientist at the level of assistant professor by providing a one-year grant of $50,000. It is generously sponsored by GlaxoSmithKline.

Recipient: Scott M. Hammond, Ph.D., University of North Carolina, Chapel Hill, N.C.
Project: The Role of microRNAs in tumorigenesis

CAREER DEVELOPMENT AWARDS
AACR Career Development Awards were first established in 1999 to provide important transitional support for direct research expenses as researchers move from the ranks of early career scientists to faculty status. Each award provides a two year grant of $50,000 per year.

AACR-Cancer Research and Prevention Foundation Career Development Award in Translational or Prevention Lung Cancer Research, given in memory of Lloyd Meeds
Recipient: Herta Huey-An Chao, M.D., Ph.D., Yale University, New Haven, Conn.
Project: The detection of pharmacodynamic changes in circulating tumor cells in response to chemotherapy using a novel robotic epifluorescent microscopy platform

AACR-Genentech BioOncology Career Development Award for Cancer

Research on the HER Family Pathway
Recipient: Jayanta Debnath, M.D., University of California, San Francisco, Calif.
Project: The role and regulation of autophagy downstream of HER family pathways

AACR-PanCAN Michael Landon Career Development Award in Pancreatic Cancer Research
Recipient: Daoyan Wei, Ph.D., The University of Texas M. D. Anderson Cancer Center, Houston, Texas
Project: The role of KLF4a in pancreatic cancer

AACR-PanCAN Career Development Award in Pancreatic Cancer Research
Recipient: David Z. Chang, M.D., Ph.D. The University of Texas M. D. Anderson Cancer Center, Houston, Texas
Project: Identification and verification of novel tumor antigens for cancer vaccine development in pancreatic carcinoma

AACR-Pennsylvania Department of Health Career Development Award in Basic Cancer Research (one-year grant)
Recipient: Edna Cukierman, Ph.D., Fox Chase Cancer Center, Philadelphia, Pa.
Project: In vivo-like 3D system to assess stroma permissiveness in tumor cell invasion

RESEARCH FELLOWSHIPS
The AACR Research Fellowships were established in 1996 in response to the growing need for additional funds to train early career scientists by providing grants of $35,000-$40,000 per year for one, two, or three years.

AACR-Genentech BioOncology Fellowship for Cancer Research on Angiogenesis
Recipient: Marco Seandel, M.D., Ph.D., Memorial Sloan-Kettering Cancer Center, New York, N.Y.
Project: Regulation of bone marrow endothelium and endothelial progenitors by androgens in prostate cancer

AACR-Amgen, Inc. Fellowship in Clinical/Translational Cancer Research
Recipient: Andrew J. Armstrong, M.D., Johns Hopkins University, Baltimore, Md.
Project: A pharmacodynamic study of pre-prostatectomy rapamycin in men with advanced localized prostate cancer

Recipient: Rupal Satish Bhatt, Ph.D., M.D., Beth Israel Deaconess Medical Center, Boston, Mass.
Project: ANGPTL4 as a potentially novel biomarker and/or therapeutic angiogenic target for renal cell cancer

AACR-MedImmune Fellowship for Research on Biologics-Based Therapies for Cancer
Recipient: Robert R. Jenq, M.D., Memorial Sloan-Kettering Cancer Center, New York, N.Y. Project: Augmentation of immune responses to melanoma DNA vaccines after allogeneic bone marrow transplantation using interleukin-7 and keratinocyte growth factor

AACR Fellowship in Clinical Cancer Research
Recipient: Catherine S. Magid Diefenbach, M.D., Memorial Sloan-Kettering Cancer Center, New York, N.Y.
Project: YKL-40: A novel serum marker for the detection of epithelial ovarian cancer and a target for tumor directed therapy

AACR-AstraZeneca-Cancer Research and Prevention Foundation Fellowship in Translational Lung Cancer Research
Recipient: Anil Potti, M.D., Duke University Medical Center, Durham, N.C.
Project: Gene expression signatures of oncogenic pathway deregulation provide a novel approach to selection of molecular targets in recurrent non-small cell lung carcinoma

AACR-Anna D. Barker Fellowship in Basic Cancer Research
Recipient: Shih-Peng Chan, Ph.D., Yale University, New Haven, Conn.
Project: Potential oncogenes encoding microRNA binding proteins

AACR-Cancer Research and Prevention Foundation Melanoma Research Fellowship, given in memory of H. Theodore Shore
Recipient: Juan Chen, M.D., University of Miami School of Medicine, Miami, Fla.
Project: Two novel laminins in the angiogenesis and progression of melanomas

FELLOWS GRANT
The Fellows Grants provides a one-year grant of $25,000 to a fellow to pursue an independent line of investigation within the context of his/her current fellowship placement.

AACR-Pennsylvania Department of Health Fellows Grant
Recipient: Sibele I. Meireles, Ph.D., Fox Chase Cancer Center, Philadelphia, Pa.
Project: Contribution of estrogen synthesis and detoxification enzyme expression to tobacco smoke-induced lung cancer

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The mission of the American Association for Cancer Research is to prevent and cure cancer. Founded in 1907, AACR is the world's oldest and largest professional organization dedicated to advancing cancer research. The membership includes more than 24,000 basic, translational, and clinicalresearchers; health care professionals; and cancer survivors and advocates in the United States and more than 60 other countries. AACR marshals the full spectrum of expertise from the cancer community to accelerate progress in the prevention, diagnosis and treatment of cancer through high-quality scientific and educational programs. It funds innovative, meritorious research grants. The AACR Annual Meeting attracts over 16,000 participants who share the latest discoveries and developments in the field. Special Conferences throughout the year present novel data across a wide variety of topics in cancer research, treatment, and patient care. AACR publishes five major peer reviewed journals: Cancer Research; Clinical Cancer Research; Molecular Cancer Therapeutics; Molecular Cancer Research; and Cancer Epidemiology, Biomarkers & Prevention.

Its most recent publication, CR, is a magazine for cancer survivors, patient advocates, their families, physicians, and scientists. It provides a forum for sharing essential, evidence-based information and perspectives on progress in cancer research, survivorship, and advocacy.


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