In peri- and postmenopausal women who have moderate to severe vasomotor symptoms associated with estrogen deficiency, data shows that HRT can be beneficial. Although the WHI results only provided data from an oral continuous therapy, researchers say that other routes may be safer and patients should discuss the option with their doctor to weigh the risks against severity of symptoms and expected benefits.
Additionally, several studies have shown that the use of HRT in patients who are survivors from gynecologic cancer does not compromise survival, as was previously thought. Several retrospective studies have failed to demonstrate an adverse effect and the establishment of a definitive role for HRT will depend on the analysis of randomized clinical trials.
This study is published in the latest issue of the International Journal of Gynecological Cancer. Media wishing to receive a PDF of the article please contact medicalnews@bos.blackwellpublishing.net.
Corresponding author Vera Loizzi, MD, is a clinical instructor in the Department of Obstetrics and Gynecology at the University of Bari, Italy. She can be reached for questions and interviews at vloizzi@tiscali.it.
About the International Journal of Gynecological Cancer
International Journal of Gynecological Cancer presents papers from throughout the global community of researchers covering many topics including basic science, epidemiology, diagnostic techniques, surgery, radiotherapy, chemotherapy, pathology and experimental studies, The Journal allows you to call on a roster of international experts for the latest research, advice, and knowledge in order to provide the best treatment for your patients.
About Blackwell Publishing
Blackwell Publishing is the world's leading society publisher, partnering with more than 600 academic and professional societies. Blackwell publishes over 750 journals and 600 text and reference books annually, across a wide range of academic, medical, and professional subjects.
Journal
International Journal of Gynecological Cancer