This symposium is based on a proposal made by Ermanno Gherardi
E. Gherardi Chairman's introduction
R. F. Doolittle, G. Spraggon and S. J. Everse
Evolution of vertebrate fibrin formation and the process of its dissolution
Discussion
E. Gherardi, R. Gonzalez Manzano, A. Cottage, K. Hawker and S. Aparicio
Evolution of plasminogen-related growth factors (HGF/SF and HGFl/MSP)
Discussion
General discussion I
Evolution of plasminogen and plasminogen-related growth
factors
F. J. Castellino and S. G. McCance
The kringle domains of human plasminogen
Discussion
T. de los Santos, J. Wang and E. Reich
Structure and function of
microplasminogen: reconstitution of microplasminogen and microplasmin from
isolated fragments
Discussion
E. Gherardi, G. Hartmann, J. Hepple, D. Chirgadze, N. Srinivasan and T. Blundell
Domain structure of hepatocyte growth factor/scatter factor (HGF/SF)
Discussion
General discussion II
HGF/SF activation
Cleavage of pro-MSP to active MSP
D. B. Rifkin, P.E. Gleizes, J. Harpel, I. Nunes, J. Munger, R. Mazzieri and I.
Noguera
Plasminogen/plasminogen activator and growth factor activation
Discussion
G. F. Vande Woude, M. Jeffers, J. Cortner, G. Alvord, I. Tsarfaty and J. Resau
Met-HGF/SF: tumorigenesis, invasion and metastasis
Discussion
A. Bardelli and P. M. Comoglio
Scatter factor receptors are key players in a
unique multistep program leading to invasive growth
Discussion
General discussion III
Heparan sulfate as a co-receptor in the HGF/SF-Met
system
A. C. E. Streit and C. D. Stern
Competence for neural induction: HGF/SF,
HGFl/MSP and the c-Met receptor
Discussion
C. Birchmeier, F. Bladt and T. Yamaai
The functions of HGF/SF and its receptor,
the c-Met tyrosine kinase, in mammalian development
Discussion
E. J. Leonard
Biological aspects of macrophage-stimulating protein (MSP) and
its receptor
Discussion
K. Matsumoto and T. Nakamura
HGF: its organotrophic role and therapeutic
potential
Discussion
E. M. Rosen, K. Lamszus, J. Laterra, P. J. Polverini, J. S. Rubin and I. D.
Goldberg
HGF/SF in angiogenesis
Discussion
W. Birchmeier, V. Brinkmann, C. Niemann, S. Meiners, S. DiCesare, H. Naundorf
and M. Sachs
Role of HGF/SF and c-Met in morphogenesis and metastasis of
epithelial cells
Discussion
General discussion IV
Angiostatin: a plasminogen-related growth inhibitor
E. Gherardi
Chairman's summing-up
Index of contributors
Subject index