After 'trying on' three placebo methods for the delivery of a rectal microbicide, study participants said they could see all of them - a douche, rectal suppository and fast-dissolving rectal insert - fitting into their daily lives. These results, which also identified the product attributes most important to participants, underscore the importance of developing a range of HIV prevention products for people who practice anal sex.
New research published in two papers by UC San Diego scientists describes novel achievements designed to make the implementation of gene drives safer and more controllable. The new split drive and home-and-rescue systems address concerns about the release of gene drives in wild populations.
A University at Buffalo-led research team is a 3D printing method called stereolithography and jelly-like materials known as hydrogels to develop a 3D printing method that's 10-50 times faster than the industry standard. The team says its progress toward 3D-printed human tissue and organs -- biotechnology that could eventually save countless lives lost due to the shortage of donor organs.
A meta-analysis finds that vision impairment and blindness are tied to an increased risk of mortality, prompting the need to address global eye health disparities.
The gene for Huntington's disease was found nearly 40 years ago, yet there are no approved treatments. A new study shows the problem may lie with slowed protein assembly.
Studies of the microbiome in the human gut have largely overlooked non-bacterial microbes: viruses, protists, archaea and fungi. Now research in mice points to a significant role for fungi, called the mycobiome, in the intestine. "We showed that the gut mycobiome of healthy mice was shaped by the environment, including diet, and that it significantly correlated with metabolic outcomes," said Kent Willis, M.D.
A study by investigators from Brigham and Women's Hospital and Exosome Diagnostics proposes a new, noninvasive way to test for transplant rejection using exosomes -- tiny vesicles containing mRNA -- from urine samples. Their findings are published in the Journal of the American Society of Nephrology.
A new study led by the University of Iowa surveyed college-aged men to test a new approach designed to reduce the risk that they engage in sexually aggressive acts or risky sexual behavior.
Using genetic engineering, researchers at UT Southwestern and Indiana University have reprogrammed scar-forming cells in mouse spinal cords to create new nerve cells, spurring recovery after spinal cord injury. The findings, published online today in Cell Stem Cell, could offer hope for the hundreds of thousands of people worldwide who suffer a spinal cord injury each year.
An ancient shift in our body's ability to conserve water may have enabled early humans to venture farther from lakes and streams in search of food. So say the authors of a study that, for the first time, measures precisely how much water humans lose and replace each day compared with our primate cousins. The research shows that the human body uses 30% to 50% less water per day than chimpanzees, gorillas, bonobos and orangutans.