With normal ageing oxidative stress increases and is involved in causing degenerative diseases like Alzheimer's disease. An ischemic stroke significantly increases oxidative stress in the brain, and this may increase the rate of neuronal degeneration. The authors hypothesize that antioxidant treatment in acute ischemic stroke, by diminishing this oxidative imbalance, may delay the onset of clinically overt dementia.
1 - patient with ischemic stroke
2 - patient who suffers an ischemic stroke and is treated with antioxidants
3 - normally ageing person