The Mdm2-binding Domain of Numb (image) Rockefeller University Press Share Print E-Mail Caption An x-ray crystallographic structure of the Numb domain that binds to Mdm2, with the crucial stretch of 11 amino acids--only present in Numb isoforms 1 and 2--shown in red. Credit : Colaluca et al., 2018 Usage Restrictions Reporters may freely use these materials in news coverage with the appropriate credit information. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.