Combining nephron progenitor cells and ureteric buds from pluripotent stem cells, with interstitial progenitor cells from a mouse embryos results in the formation of kidney higher-order structures.
[This image has been modified from the original graphical abstract of the following article: Taguchi, A., & Nishinakamura, R. (2017). Higher-Order Kidney Organogenesis from Pluripotent Stem Cells. Cell Stem Cell, 21(6), 730-746.e6. doi:10.1016/j.stem.2017.10.011]