Comparison Between Normal and Hypertrophic Heart (image) Institute for Basic Science Share Print E-Mail Caption A mutation causes the thickening of the muscle wall, which reduces the blood flow. Credit (Credits: Blausen.com staff (2014). Medical gallery of Blausen Medical 2014. WikiJournal of Medicine 1 (2)) Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.