Figure 1 (IMAGE)

Institute for Basic Science

Figure 1

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Left) Reactive astrocytes express a high level of MAOB and release a high level of GABA, which results in the inhibition of GABRA5 neurons. This results in decreased thermogenesis in brown fat tissues, and an increase in white fat storage. Right) When the GABRA5 neuron activity is restored, brown fat thermogenesis is increased and white fat storage is decreased. In both cases, mice are fed a high-fat diet.

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Institute for Basic Science

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