Membrane modification of photosynthetic bacteria for enhanced cancer therapy (IMAGE)

Japan Advanced Institute of Science and Technology

Membrane modification of photosynthetic bacteria for enhanced cancer therapy

Caption

The membranes of photosynthetic bacteria were PEGylated to improve their biocompatibility and photothermal conversion. Fluorescent markers and an anti-PD-L1 antibody were further attached to enable tumor-targeting and immunological activation. The engineered bacteria demonstrated effective tumor suppression and immunological responses in a mouse model of colon cancer.

Credit

Eijiro Miyako from JAIST.

Usage Restrictions

Can be reused with attribution

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.