Childhood cancer: "New" immune system responds better to therapy (IMAGE)

St. Anna Children's Cancer Research Institute

Childhood cancer: "New" immune system responds better to therapy

Caption

Scientists at St. Anna Children's Cancer Research Institute and the Eberhard Karls University of Tübingen have shown that immunotherapy after stem cell transplantation effectively combats certain pediatric nerve tumors (i.e, neuroblastomas, see image). Crucially, stem cells from a parent provide children with a new immune system that responds much better to immunotherapies. These results of an early clinical trial were published in the prestigious Journal of Clinical Oncology. >> https://ascopubs.org/doi/10.1200/JCO.22.01630 The image shows MYCN-amplified neuroblastoma cells

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Sabine Taschner-Mandl group/St. Anna CCRI

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