Alzheimer's disease mutant organoid (IMAGE) International Society for Stem Cell Research Caption Human 3D cortical spheroid with a PSEN1 mutation. Credit Erin Hurley, University of Texas at San Antonio Usage Restrictions Use with credit. License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.