Schematic diagram to show the mechanism of CD69 action on the stem-like and terminally differentiated CD8+ T cells in wild-type and CD69-deficient mice (IMAGE)

Chiba University

Schematic diagram to show the mechanism of CD69 action on the stem-like and terminally differentiated CD8+ T cells in wild-type and CD69-deficient mice

Caption

A study to describe the functional mechanism of CD69 in regulating the tumor-specific CD8+ T cell fate in tumor-draining lymph nodes (TDLNs), which can be used to develop a novel anti-CD69 antibody for more efficient cancer immunotherapies in the future

Credit

Ryo Koyama-Nasu and Motoko Y. Kimura from Chiba University

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