Figure 1. Overview of the screening approach (IMAGE)
Caption
The proposed method involves using water microdroplets as tiny bacterial cultures and bioreactors and then sorting them based on their fluorescence intensity. The Q-bodies are designed to become fluorescent upon binding to a target protein. Thus, fluorescence intensity is directly related to the amount of the desired protein that each bacterial strain can produce.
Credit
Associate Prof. Tetsuya Kitaguchi
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CC BY-NC-ND