Liver cells control our biological clock (IMAGE)
Caption
A “humanised” mouse model receives liver cells from healthy mice (control group) or human liver cells (humanised mice). The presence of human liver cells leads to a modification in the circadian clock of the liver and muscle and affects the central clock (the suprachiasmatic nuclei). This results in a phase advance in circadian rhythm in the humanised animal, the metabolism and behaviour of which shifts forward by a few hours.
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© Luquet et al./ Science Advances
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