Developments in biochemical and biophysical technology in recent decades have made it easier to observe the molecular structures of proteins and enzymes. (IMAGE)
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Conformational changes experienced by proteins play an important role in their biological function and in enzyme catalysis. Professor Nicolas Doucet's team is trying to elucidate how these dynamic events affect their molecular function, in addition to deciphering their evolutionary conservation among several homologous proteins and enzymes. These studies will help refine the development of new specific inhibitors in a therapeutic context.
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Nicolas Doucet (INRS)
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