Lentivirus vector shows promise as potential treatment for Duchenne muscular dystrophy (IMAGE)

Cincinnati Children's Hospital Medical Center

Lentivirus vector shows promise as potential treatment for Duchenne muscular dystrophy

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Researchers showed that systemic delivery of Mymk+Mymg-LV-Dys resulted in a significant level of Dys+ myofibers. Importantly, the team did not detect evidence of viral transduction in non-skeletal muscle tissues including heart, kidney, liver, and spleen. Dystrophic mice exhibited healthier muscles (reductions in muscles cells where a dye was able to enter) after treatment with Mymk+Mymg-LV-Dys.

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Cincinnati Children's Hospital Medical Center

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