(IMAGE)
Caption
The Developmental Origins of Health and Disease (DOHaD) theory refers to the concept that maternal and environmental variables at a very early life stage can influence a child's growth, development and health in later life. Maternal and early-life high-fat diets increase preference for salty taste, while there are no differences in bitter, sour, sweet, and umami tastes. The protein and gene expression of Angiotensin II receptor type 1 (AT1) in the taste buds of female offspring exposed to a high-fat diet is increased three weeks after birth. AT1 in taste bud cells relates to salty taste perception, and increasing AT1 in offspring's taste bud cells affects the taste preference by increasing sodium intake.
Credit
Department of Orthodontic Science, TMDU
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