3D RENDERING (IMAGE) Weill Cornell Medicine Caption Synapses are composed of presynaptic and postsynaptic terminals (blue) and are contacted by astrocytes (purple), a crucial non-neuronal cell type. Dementia-associated protein buildup in astrocytes causes abnormal release of immune factors (orange) that disturb presynaptic function and cause neuronal hyperactivity and cognitive decline in mice Credit Original 3D by BROKENGRID Usage Restrictions NONE License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.