structure of DNA-repair enzyme polymerase theta (IMAGE)

Rice University

structure of DNA-repair enzyme polymerase theta

Caption

The structure of DNA polymerase theta, which serves to fix double-strand breaks in DNA (at top) by bridging the hanging single-stranded ends and catalyzing DNA synthesis across the break. Researchers from Rice University and St. Jude Children’s Research Hospital in Memphis, Tennessee, studied the enzyme’s role in a process known as microhomology-mediated end joining and discovered it could be a promising target for precision cancer therapy. (Credit: Illustration by Chuxuan Li/Gao Lab)

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Illustration by Chuxuan Li/Gao Lab

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Must credit: Chuxuan Li/Gao Lab

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