(IMAGE)

ICFO-The Institute of Photonic Sciences

Caption

Mature dendritic cell expressing Siglec-1 nanoclusters (green dots) on the cell surface a few minutes after capture of HIV-like particles (red dots). Right: Massive transformation of the dendritic cell morphology after 60 min of HIV engagement. Green corresponds to Siglec-1 nanoclusters, Cyan corresponds to HIV particles. Engagement of Siglec-1 nanoclusters with HIV particles leads to the formation of an actin-enriched ring structure that accumulates Siglec-1 and HIV particles together into a sack-like compartment.

Credit

ICFO

Usage Restrictions

Credit must be given to the creator. Only noncommercial uses of the work are permitted.

License

CC BY-NC

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.