Uncovering hidden mitochondrial mutations in single cells (IMAGE)

King Abdullah University of Science & Technology (KAUST)

Uncovering hidden mitochondrial mutations in single cells

Caption

A human blastocyst-like synthetic embryo called blastoid showing the presence of an enveloping layer of extra-embryonic cells, a blastocoel-like cavity, epiblast cells (green, giving rise to the future embryo) and hypoblast cells (red, giving rise to the future amnion). iMiGSeq was used to sequence mtDNA in a single blastoid to model the dynamics of mtDNA mutations during human embryogenesis.

Credit

© 2023 KAUST; Mo Li.

Usage Restrictions

None. Please credit.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.