Fitness landscape. (IMAGE) University of Tokyo Caption This topographical “map” shows the step-by-step development of E. coli’s resistance to tetracycline, a common antibiotic used to treat a wide variety of infections. The bacteria at the peak of the “mountains” (in red) have the best fitness and most likely chance of resisting the effects of the antibiotic. Credit Modified from 2022 Iwasawa et al. Usage Restrictions Credit must be given to the creator. License CC BY Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.