Lenze with medications (IMAGE) WashU Medicine Caption Eric J. Lenze, MD, holds an antidepressant drug in one hand and aripiprazole, originally approved as an antipsychotic, in the other. Lenze, head of the Department of Psychiatry at Washington University School of Medicine in St. Louis, led a multicenter study that found, in older adults with treatment-resistant depression, that augmenting an antidepressant drug with aripiprazole helped a significant number of patients. Credit Matt Miller-Washington University Usage Restrictions None License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.