Jumbo Phage Infects a Bacterium (IMAGE)

University of California - San Diego

Jumbo Phage Infects a Bacterium

Caption

A jumbo phage infects a bacterium. A nucleus-like compartment (green) is formed to protect the newly synthesized phage genomes from bacterial defense systems. The capsids (gray) of the new phage travel along filaments called PhuZ (yellow) to be delivered to the nucleus where they dock in order to package phage DNA. Eventually, the bacterial cell lyses and the new phage emerge ready to infect new bacteria.

Credit

Credit: Margot Riggi, Iwasa Lab, University of Utah. Copyright Elizabeth Villa and Joe Pogliano, UC San Diego

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Must be used in conjunction with HHMI grant story on jumbo phages for antibiotic resistance.

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