(IMAGE)

Doshisha University

Caption

Researchers from Doshisha University suggest that a transcription factor “Nrf3” coordinates the melanogenesis pathway in response to forskolin or αMSH via macropinocytosis and autophagy. They also indicate that nelfinavir inhibited Nrf3-mediated melanogenesis.

Credit

Image courtesy: Tsuyoshi Waku from Doshisha University

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