Radiotherapy causes cardiac tissue toxicity (IMAGE)
Caption
Six months after radiotherapy, activation of the cGAS–STING inflammatory signaling pathway leads to an accumulation of fibrotic scarring (blue) in the heart muscle of mice, ultimately leading to reduced cardiac function and heart failure.
Credit
© 2022 Shamseddine et al. Originally published in Journal of Experimental Medicine. https://doi.org/10.1084/jem.20220809
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