Potency of sphaerimicin analogs (IMAGE)

Hokkaido University

Potency of sphaerimicin analogs

Caption

The sphaerimicin analogs (SPMs) inhibit the activity of MraY, and hence the replication of bacteria, with different degrees of effectiveness. The potency of the analog increases as the IC50 decreases (Takeshi Nakaya, et al. Nature Communications. December 20, 2022).

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(Takeshi Nakaya, et al. Nature Communications. December 20, 2022)

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