Image (IMAGE) Tokyo Medical and Dental University Caption Top, SETD1A, directly recruited to the RUVBL1 promoter, enhances RUVBL1 gene expression by increasing H3K4me3 levels in pancreatic cancer cells. Bottom, High co-expression of SETD1A and RUVBL1 can predict worse prognosis than others. Credit Department of Molecular Oncology, TMDU Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.