New study finds promising treatment for cognitive deficits associated with cholestatic liver disease (IMAGE)

Elsevier

New study finds promising treatment for cognitive deficits associated with cholestatic liver disease

Caption

Cellular integrity of the blood brain barrier (BBB) is compromised during cholestasis resulting in cognitive deficits in some cholestatic animals. This is normalized by obeticholic acid (OCA) therapy, which reduces memory deficits and reverses both neuronal and liver senescence.

Credit

The American Journal of Pathology

Usage Restrictions

Please include attribution.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.