caslon release, gastro cancer (IMAGE) Johns Hopkins Medicine Caption Image of human gastroesophageal junction-derived organoid, modified by dual-knockout of key tumor suppressor genes (TP53/CDKN2A) using CRISPR/Cas9 gene editing technology, which caused cells to become more cancerous. Credit Photo courtesy of Stephen Meltzer, M.D. Usage Restrictions -- License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.