Spike glycoprotein structure of SARS-CoV (IMAGE)

University of Bristol

Spike glycoprotein structure of SARS-CoV

Caption

Spike glycoprotein structure of SARS-CoV, the coronavirus causing the 2002 outbreak. When linoleic acid is bound, the structure is locked in a non-infectious form. The cryo-EM density, calculated by cloud computing, is shown (left) along with the protein structure (middle). Linoleic acid molecules are coloured in orange. A zoom-in of the pocket (boxed), conserved in all deadly coronaviruses, is shown

Credit

Christiane Schaffitzel and Christine Toelzer, University of Bristol

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