Disrupting phase separation had no effect on germline health or fertility (IMAGE)

MDI Biological Laboratory

Disrupting phase separation had no effect on germline health or fertility

Caption

Super-resolution image of a nucleolus in a live, wild-type C. elegans nematode, left, shows well-organized architecture of interior condensates. At right, when a newly discovered coding gene called NUCL-1 is disrupted in a mutant worm, the architecture falls apart. Contrary to some thinking about the function of nucleolus substructures, both wild-type and mutant worms were healthy, developed normally, and retained fertility.

Credit

Emily Spaulding, Ph.D., MDI Biological Laboratory

Usage Restrictions

Please provide full credit when re-using

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.