Sodium–potassium–chloride transporter NKCC1 (IMAGE)

Aarhus University

Sodium–potassium–chloride transporter NKCC1

Caption

The Na+-K+-2Cl− cotransporter NKCC1 (SLC12A2) performs Na+-dependent uptake of Cl− and K+ ions and is an important factor in ion homeostasis and osmotic control. Its mechanisms of ion recognition and release are addressed here by cryo-EM microscopy, ion uptake studies, and molecular dynamics simulations.

Credit

Caroline Neumann and Poul Nissen, Aarhus University

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Image may be used only to illustrate the research described in the accompanying release.

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