Cryo-EM structure of engineered priming immunogen (IMAGE)

Scripps Research Institute

Cryo-EM structure of engineered priming immunogen

Caption

Scripps Research and collaborators demonstrate the first steps in an HIV vaccine approach that aims to prompt the creation of highly protective broadly neutralizing antibodies. Pictured is the cryo-EM structure of the engineered priming immunogen (grey, black); a key feature of the HIV spike protein called glycans (green); and the precursor antibody (purple and pink) that it binds to with high affinity.

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Scripps Research

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