Key Signaling Pathway in Immune Cells Could be New Alzheimer’s Target (IMAGE)

Weill Cornell Medicine

Key Signaling Pathway in Immune Cells Could be New Alzheimer’s Target

Caption

Microglial NF-kB accelerates the seeding and spread of tau aggregates in the cortex of mice inoculated with tau seeds. Depleting microglia (top right) or inhibiting microglia NF-kB (bottom right) diminished the amount of tau aggregates. (Controls are shown on the left.)

Credit

Dr. Li Gan

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