Graphical representation of dopamine-driven neuronal excitability via KCNQ channel phosphorylation for reward behavior (IMAGE)

Fujita Health University

Graphical representation of dopamine-driven neuronal excitability via KCNQ channel phosphorylation for reward behavior

Caption

The schematic demonstrates the mechanism by which dopamine-triggered ERK pathway controls the excitation of medium spiny neurons in the nucleus accumbens via voltage-gated potassium channel KCNQ2 phosphorylation, thereby promoting reward behavior in mice

Credit

Dr. Kozo Kaibuchi and Dr. Daisuke Tsuboi from Fujita Health University Image Link: https://linkinghub.elsevier.com/retrieve/pii/S2211124722011330

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