Deciphering the dynamics of the ovarian reserve in cynomolgus monkey (IMAGE)

Science China Press

Deciphering the dynamics of the ovarian reserve in cynomolgus monkey

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Graphical abstract of this study. A total of 18 ovaries from 16 cynomolgus monkeys were collected and separated into five developmental stages: perinatal period (E140, 8-day-old [8 d]), preadolescence (1–3 years), adolescence (4–5 years), adulthood (6–15 years), and perimenopause (16–23 years). Immunofluorescent staining and H&E staining of ovaries were performed to investigate the dynamics of the cynomolgus monkey ovarian reserve and the establishment of the primordial follicle pool. Serum samples were collected to analyze the hormone levels.

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