PTP1B and lung inflammation in mice (IMAGE)

Cold Spring Harbor Laboratory

PTP1B and lung inflammation in mice

Caption

CSHL researchers have found treating mice with a drug candidate that inhibits a protein called PTP1B can prevent deadly lung inflammation in mice. Seen here are 3D images of mouse lungs treated with (left) and without (right) the PTP1B inhibitor drug candidate. The drug candidate prevented a lethal amount of lung damage, shown in cyan, from overactive immune cells called neutrophils.

Credit

Tonks lab/CSHL, 2022

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