(IMAGE) Tokyo Medical and Dental University Caption The expression of Pthlh, Smoc2 Runx2, Ibsp and Spp1, those of which are involved in ossification, was up-regulated in the Mkx-expressing cell population (A) and osteoblast population (B) of Mkx-deficient (Mkx-/-) rats. Credit Department of Systems BioMedicine, TMDU Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.