Structural model of active PI3KC2α at the plasma membrane. (IMAGE)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie

Structural model of active PI3KC2α at the plasma membrane.

Caption

Structural model of active PI3KC2α at the plasma membrane. In this open conformation the distal PX and C2 domains associate with plasma membrane lipids, while the Ras-binding domain (RBD) binds to a so far unknown Rab protein.

Credit

Wen-Ting Lo, FMP

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License

CC BY

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