CF Airways - ASO Treatment (IMAGE)

Rosalind Franklin University of Medicine and Science

CF Airways - ASO Treatment

Caption

Cystic fibrosis is caused by mutations in the cystic fibrosis transmembrane regulator (CFTR) gene that disrupt normal CFTR expression and function as a membrane chloride channel, leading to thick mucus buildup in the airways of the lungs. Antisense oligonucleotide (ASO) treatment modifies CFTR gene expression leading to increased expression of a modified protein with retained channel function (CFTR*).

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Michelle Hastings has been granted a license to use the BioRender content, including icons, templates and other original artwork, appearing in the attached completed graphic pursuant to BioRender's Academic License Terms.

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