LAMZ augments muscle and bone by mimicking calcium signaling to induce PGC-1α (IMAGE)

Tokyo Medical and Dental University

LAMZ augments muscle and bone by mimicking calcium signaling to induce PGC-1α

Caption

Exercise induces calcium signaling in the muscle and bone. Under this signaling, PGC-1α is activated, resulting in the augmentation of these tissues. LAMZ, a newly identified locomomimetic drug was found to facilitate the calcium signaling pathway and restores locomotor fitness.

Credit

Department of Cell Signaling, TMDU

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