Understanding how methionine regulates the differentiation of pluripotent stem cells (IMAGE)

Tokyo Institute of Technology

Understanding how methionine regulates the differentiation of pluripotent stem cells

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Differentiation of pluripotent stem cells (PSCs) is regulated through a methionine-mediated mechanism, which has now been pinpointed by Tokyo Tech researchers. They have revealed that zinc (Zn) plays a crucial role in PSC potentiation. They used these insights to design a protocol to convert PSCs into insulin-producing pancreatic β cells—a high-potential diabetes therapy.

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Prof. Shoen Kume from Tokyo Institute of Technology

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