Graphic abstract. (IMAGE) Tampere University Caption Graphic abstract. Mice deficient in the IL-13 receptor (IL-13R1 KO) developed more skin cancers and had elevated levels of regulatory T cells, IL-2 and TSLP cytokines. IL-22 cytokine levels were reduced in the skin. Graph: Tero Järvinen. The figure was created by BioRender.com Credit Tero Järvinen. The figure was created by BioRender.com Usage Restrictions Credit must be given to the creator. Only noncommercial uses of the work are permitted. No derivatives or adaptations of the work are permitted. License CC BY-NC-ND Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.