NPHP5-deficient retinal organoids (IMAGE) NIH/National Eye Institute Caption Treating patient-derived retinal organoids with AAV-NPHP5 restores rhodopsin localization in photoreceptor outer segments. Top: Retinoids stained for DNA (blue), NPHP5 (red), and rhodopsin (green). Below: Close-up view of organoid photoreceptor layer stained green for rhodopsin. Adapted from Kruczek et al, 2022. Credit Anand Swaroop, Ph.D. and Kamil Kruczek, Ph.D., National Eye Institute Usage Restrictions No restrictions. License Public Domain Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.