Lightsheet microscope movie of clarified mouse gut in cross-section showing architecture of the colon. (VIDEO)
Caption
Movie showing reconstruction of full circumferential cross-sections obtained from a 3cm long segment of the gut cleared with iDisco+ protocol. The autofluorescence signal at 10x magnification acquired with Clarity Optimised Lightsheet Microscopy clearly shows the architecture of the colon with crypts of the colonic mucosa on the inside of each slice surrounded by submucosa and a ring of circular and longitudinal muscles. Data processed with Imaris software.
Credit
Wyss Center for Bio and Neuroengineering
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License
CC BY-NC-ND