α-synuclein aggregates as seen on a PET scan in patients with MSA and a healthy control (IMAGE)
Caption
White arrows indicate accumulation of 18F-SPAL-T-06, suggesting α-synuclein aggregates in the putamen, yellow arrows in the pons, yellow triangle in the cerebellar white matter, and white triangle in the peduncles. On the other hand, red arrows indicate accumulation of 18F-SPAL-T-06 in the choroid plexus outside the brain tissues, which is considered independent of α-synuclein aggregates. MSA-P: multiple system atrophy with predominant parkinsonism; MSA-C: multiple system atrophy with predominant cerebellar ataxia.
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Makoto Higuchi, National Institutes for Quantum Science and Technology
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