fig 1 (IMAGE) Compuscript Ltd Caption The effects of TMAO and urea on the rate of labeling of sulfhydryl groups of glutamate dehydrogenase by the reagent 4-chloro-7-nitrobenzofurazan (Nbf-Cl). Control mixtures had neither TMAO nor urea. The structures of TMAO and urea are shown to the right of the graph. (Figure redrawn after Yancey PH, Somero GN (1979) Counteraction of urea destabilization of protein structure by methylamine osmoregulatory compounds of elasmobranch fishes. Biochem J 182:317–323) Credit MLST Usage Restrictions Credit must be given to the creator. License CC BY Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.