Mice with KCNMA1 ion channel mutations like that of the genetic disorder (IMAGE)

University of Maryland School of Medicine

Mice with KCNMA1 ion channel mutations like that of the genetic disorder

Caption

Mice genetically engineered to carry mutations that make the KCNMA1 ion channel more active (left) are hunched and immobilized after a stress test which triggers involuntary immobility; normal mice (middle) show typical mouse behavior, and those with a mutation causing reduced KCNMA1 ion channel activity appear restless.

Credit

Cooper Roache and Andrea Meredith

Usage Restrictions

include credit information

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.